Table 2.
Deuterium enrichment in body water and in protein-bound alanine in serum and in various tissues
| Days on 8% Volume 2H2O | Body Water | Serum Protein | Liver | Soleus Mix | LV Myofibrillar | LV Collagen | Tendon |
|---|---|---|---|---|---|---|---|
| 42# | 4.69 ± 0.20 | 5.24 ± 0.11 | 5.22 ± 0.08 | 5.20 ± 0.07 | 4.93 ± 0.11 | 4.77 ± 0.06 | 4.29 ± 0.05 |
| 49## | 4.86 ± 0.11 | 5.63 ± 0.08 | 5.43 ± 0.06 | 5.29 ± 0.09 | 5.06 ± 0.07 | 4.93 ± 0.06 | 4.52 ± 0.01 |
| 56 | 5.47 ± 0.06 | 6.01 ± 0.12 | 5.88 ± 0.14 | 5.80 ± 0.08 | 5.46 ± 0.11 | 5.25 ± 0.07 | 4.84 ± 0.09 |
| 63 | 5.60 ± 0.16 | 5.66 ± 0.04 | 5.56 ± 0.03 | 5.84 ± 0.03 | 5.24 ± 0.05 | 5.05 ± 0.02 | 4.78 ± 0.06 |
Values are means ± SE; n = 4/time point. LV, left ventricle. Alanine 2H enrichments (%) are E = E[M + 1]/nH, where nH = 4 for alanine. Protein fractions are serum protein (mainly albumin), liver mix (midlobe nonsoluble liver proteins), LV myofibrillar (heart left ventricle myofibrillar proteins), LV collagen (heart left ventricle collagen proteins), and tendon (patella tendon collagen protein fraction). #Enrichments on day 42 were different from enrichments on days 56 and 63; ##enrichments on day 49 were different from enrichments on day 56.