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. 2013 Feb 13;304(8):F1054–F1065. doi: 10.1152/ajprenal.00650.2012

Fig. 5.

Fig. 5.

IR-induced infiltration of macrophages and PDGF receptor (PDGFR)-β expression is suppressed in netrin-1 transgenic animal kidney. Immunohistochemical localization of macrophages and PDGFRβ was carried out as described in materials and methods. A few interstitial macrophages and low levels of PDGFRβ expression are seen in sham-operated WT and netrin-1 transgenic animals. A large increase in the number of interstitial macrophages (arrows) and in PDGFRβ expression after IR in WT mouse kidney was seen, which was inhibited in netrin-1 transgenic animal kidney. Magnification ×400. Scale bar = 100 μM.