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Filtration fraction (FF). A: male intact and gonadectomized control and IUGR rats. B: female intact and gonadectomized control and IUGR rats. FF was measured at 16 wk of age in chronically instrumented, conscious animals pretreated with enalapril (250 mg/l for 1 wk) at 3 time points: baseline, during acute Ang II (100 ng·kg−1·min−1), and during acute Ang II plus the Rho kinase antagonist fasudil (33 μg·kg−1·min−1). Values represent means ± SE.
