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Diabetes decreased cytochrome oxidase activity and subunit 3 and 4 expression in the diabetic LV. A: cytochrome oxidase activity was determined by oxidation of reduced cytochrome c as described in methods (98). SSF, subsarcolemmal fraction; IMF, intermyofibrillar fraction. B: quantification of subunit 3 and 4 in LV. Values are means ± SE: *P < 0.05, #P < 0.10 compared with Wistar control.
