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. 2013 Feb 15;304(8):H1159–H1165. doi: 10.1152/ajpheart.00903.2012

Fig. 3.

Fig. 3.

Angiogenic potential restored by chronic AICAR administration in RUPP rats. A: angiogenic potential was increased (P < 0.05) with chronic AICAR (50 mg/kg twice a day) treatment in the RUPP compared with the untreated RUPP. No statistical difference was observed between NP, NP + A, and RUPP + A. B: direct AICAR (DA) treatment onto human umbilical vascular endothelial cells treated with NP or RUPP serum had no effect on angiogenic potential. *P < 0.05, different from NP; †P < 0.05, different from RUPP. Data presented as means ± SE; n = 8 RUPP, 8 NP, 6 NP + A, and 8 RUPP + A.