Table 4.
Year of Child’s Birth | Unadjusted | Adjusted, traditional outcome regression modela |
Adjusted, marginal structural model with IPWa |
Adjusted, doubly robust estimation modelb |
---|---|---|---|---|
1997 (n=24) | --c | --c | --c | --c |
1998 (n=6,779) | 1.12 [0.75–1.68] | 1.18 [0.61–2.26] | 1.34 [0.70–2.54] | 1.32 [0.68–2.55] |
1999 (n=11,298) | 1.29 [0.96–1.74] | 1.18 [0.78–1.77] | 1.17 [0.78–1.77] | 1.17 [0.78–1.77] |
2000 (n=13,131) | 1.33 [1.00–1.76] | 1.46 [1.01–2.11] | 1.48 [1.02–2.15] | 1.48 [1.02–2.15] |
2001 (n=11,319) | 1.08 [0.79–1.48] | 0.79 [0.49–1.28] | 0.80 [0.49–1.30] | 0.79 [0.48–1.29] |
2002 (n=9,136) | 1.39 [1.00–1.92] | 1.32 [0.86–2.00] | 1.34 [0.88–2.03] | 1.33 [0.87–2.03] |
2003 (n=993) | 0.85 [0.27–2.70] | 5.17 [0.52–51.41] | 3.43 [0.37–32.20] | --c |
Combined (n=52,680) | 1.23 [1.07–1.41] | 1.21 [0.99–1.46] | 1.23 [1.01–1.49] | 1.22 [1.00–1.49] |
Adjustment model or IPW included mother's cell phone use during pregnancy, alcohol use during pregnancy, smoking during pregnancy, fever during pregnancy, mother's age, social-occupational status, breast feeding, ear infection by age 18 months, sex of child, and gestational age at birth, and reduced hearing at age 18 months.
Doubly robust estimation combining covariate adjustment in the traditional outcome regression with IPW application in a marginal structural model using adjustment scheme.
Insufficient sample size