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TNF-α and IL-1β mRNA expression in BAL macrophages isolated from guinea pigs treated with parathion. RNA was isolated from BAL macrophages collected from guinea pigs 24 h after administration of parathion (1.0 mg/kg, s.c.) or an equal volume of peanut oil (vehicle control). As determined by qPCR, parathion significantly increased TNF-α (A) and IL-1β (B) mRNA expression in BAL macrophages (n = 5–7). Data are presented as means ± SE (*P ≤ 0.05).
