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. 2013 Feb 22;27(4):487–494. doi: 10.1038/eye.2013.10

Table 2. Odds ratio for of self-reported glaucoma by supplemental intake of vitamins A, C, and E.

  Unadjusted
Adjusted model Aa
Adjusted model Bb
Adjusted model Cc
  OR 95% CI P-trend OR 95% CI P-trend OR 95% CI P-trend OR 95% CI P-trend
Vitamin A
 No consumption 1.00   0.742 1.00   0.878 1.00   0.638 1.00   0.286
 Firstquartile (≤2500 IU/day) 0.56 0.22–1.47   0.58 0.22–1.55   0.60 0.23–1.58   0.55 0.20–1.49  
 Second quartile (>2500 IU/day) 1.04 0.40–2.70   1.01 0.39–2.58   0.98 0.36–2.65   0.97 0.31–3.05  
 Third quartile (>3500 IU/day) 1.51 0.65–3.50   1.60 0.65–3.93   1.48 0.58–3.77   1.08 0.32–3.67  
 Fourth quartile (>6333 IU/day) 0.98 0.38–2.55   0.78 0.29–2.09   0.69 0.23–2.03   0.48 0.13–1.82  
                         
Vitamin C
 No consumption 1.00   0.556 1.00   0.608 1.00   0.447 1.00   0.227
 First quartile (≤100 mg/day) 0.35 0.130.92   0.33 0.130.83   0.34 0.140.81   0.34 0.130.87  
 Second quartile (>100 mg/day) 1.76 0.90–3.44   1.77 0.90–3.47   1.72 0.88–3.35   1.38 0.76–2.50  
 Third quartile (>500 mg/day) 1.57 0.73–3.37   1.14 0.50–2.60   1.10 0.48–2.54   0.97 0.42–2.25  
 Fourth quartile (>900 mg/day) 0.63 0.36–1.10   0.53 0.290.95   0.48 0.260.91   0.47 0.230.97  
                         
Vitamin E
 No consumption 1.00   0.004 1.00   0.065 1.00   0.052 1.00   0.098
 First quartile (≤30 IU/day) 0.40 0.14–1.17   0.52 0.17–1.58   0.54 0.17–1.72   0.63 0.20–1.97  
 Second quartile (>30 IU/day) 1.26 0.68–2.34   1.34 0.67–2.67   1.38 0.68–2.81   1.36 0.67–2.79  
 Third quartile (>96 IU/day) 1.40 0.95–2.06   1.00 0.65–1.55   0.97 0.63–1.47   1.01 0.64–1.60  
 Fourth quartile (>400 IU/day) 3.40 1.587.33   3.20 1.297.89   3.15 1.297.72   2.59 0.89–7.56  

Bold values represent ORs or trend P-values which are statistically significant.

a

Model A adjusted for age.

b

Model B adjusted for age and demographic variables of sex, race, annual household income, and education level.

c

Model C adjusted for age, demographic variables, and HRB of smoking (current, past, never) and alcohol intake (number of drinks per day), self-reported general health condition, and self-reported diabetic retinopathy.