Table 4.

Characteristics and renal function Mean ± SEM in pigs with minor and major collaterals with similar degrees of renal artery stenosis

Parameter	Minor collaterals, n = 6	Major collaterals, n =8
Body weight, kg	45.6±2.9	49.8±2.9
Collateral index, %	0.15±0.02	0.47±0.03*
Degree of stenosis, %	83.3±4.0	89.1±3.4
Serum creatinine, mg/dl	1.63±0.10	1.75±0.08
Systemic plasma renin activity, ng/ml/h	4.7±4.4	10.5±4.6
Systolic blood pressure, mm Hg	133±5	160±9*
Diastolic blood pressure, mm Hg	104±4	126±7*
Stenotic kidney
Renal cortical volume, cc	93.0±6.4**	63.3±9.3*, **
Cortical perfusion, ml/min/cc tissue	4.6±0.9	3.2±0.4**
Renal medullary volume, cc	12.0±2.4	11.9±1.6**
Medullary perfusion, ml/min/cc tissue	2.5±0.7	1.8±0.3
Renal blood flow, ml/min	445±83	244±59*, **
Renal vascular resistance, mm Hg/ml*min–1	0.61±0.39	0.87±0.29**
Glomerular filtration rate, ml/min	65±6	43±7*, **
Contralateral kidney
Renal cortical volume, cc	121.6±13.2	143.0±12.7
Cortical perfusion, ml/min/cc tissue	5.6±0.5	4.4±0.4*
Renal medullary volume, cc	13.5±3.1	24.4±23.8*
Medullary perfusion, ml/min/cc tissue	3.9±0.7	2.3±0.4*
Renal blood flow, ml/min	732±107	674±52
Renal vascular resistance, mm Hg/ml*min–1	0.17±0.02	0.21±0.02
Glomerular filtration rate, ml/min	88±9	102±8

*P < 0.05 vs minor collaterals; **P < 0.05 vs contralateral kidney.