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. 2013 Jan 18;177(4):351–360. doi: 10.1093/aje/kws234

Table 2.

P Value and Effect Estimate for Selected Markers Across Ethnic Groups and Models in the Ongoing Children's Health Study

Marker Allele Local Strataa Non-Hispanic Whites
Hispanics
Combinedb
No.c Allele Frequency Model 3d
No. Allele Frequency Model 3
Model 4e
No. Allele Frequency Model 3
Model 4
Inline graphic P Value Inline graphic P Value Inline graphic P Value Inline graphic P Value Inline graphic P Value
rs10119122 G L ≈ 0 0 12 0.46 0.03 12 0.46 0.04
L ≈ 1 0 410 0.60 −0.17 410 0.60 −0.17
L ≈ 2 1,372 0.66 721 0.64 −0.37 2,093 0.65 −0.37
All 1,372 0.66 −0.36 2.1 × 10−5 1,143 0.62 −0.30 1.8 × 10−3 4.7 × 10−3 2,515 0.64 −0.34 4.5 × 10−8 1.6 × 10−7
rs10519951 T L ≈ 0 0 119 0.34 −1.12 119 0.34 −1.17
L ≈ 1 0 531 0.26 −0.48 531 0.26 −0.49
L ≈ 2 1,386 0.19 510 0.19 0.16 1,896 0.19 0.18
All 1,386 0.19 0.19 7.1 × 10−2 1,160 0.24 −0.29 5.2 × 10−3 1.6 × 10−5 2,546 0.21 −0.05 5.0 × 10−1 8.5 × 10−7

a Estimated individual local ancestry. L is rounded up into 3 categorical groups: 0 Inline graphic; 1 (Inline graphic > 0.5–1.5); and 2 (Inline graphic > 1.5).

b Combined non-Hispanic white and Hispanic samples for analysis.

c Sample size within each local stratum.

d Effect estimate Inline graphicof the single-nucleotide polymorphism marginal effect followed by the corresponding P value from model 3: YG + Q + L.

e The expected effect estimate Inline graphicof the single-nucleotide polymorphism effect within each local stratum followed by the 2-df test P value from model 4: YG + L + GL + Q.