Figure 1a: Diagnostic approach for patients presenting with reflux symptoms (modified from Kahrilas and Smout2 ) 1 EOE=eosinophilic esophagitis; 2 EGJOO=esophagogastric junction outflow obstruction; 3 DES=diffuse esophageal spasm
Figure 1b: Empiric proton pump inhibitor therapy for patients with reflux symptoms (modified from Tytgat et al.9)
Figure 1c: Ambulatory reflux monitoring algorithm for PPI non-responders (modified from Richter et al.48)