TABLE II.
Logistic regression model of biomarkers versus eosinophil status in BOBCAT (n = 59)
Estimate | SE | z Score | P value | |
---|---|---|---|---|
Age | −0.0396 | 0.039 | −1.015 | .31 |
Sex (male) | −0.2031 | 0.889 | −0.229 | .82 |
Body mass index | −0.1004 | 0.066 | −1.527 | .13 |
Blood eosinophils | 1.7482 | 3.621 | 0.483 | .63 |
Serum IgE | −0.0002 | 0.001 | −0.100 | .92 |
Feno | 0.0476 | 0.038 | 1.238 | .22 |
Serum periostin | 0.2491 | 0.092 | 2.719 | .007 |
We applied a logistic regression model to evaluate demographic and biomarker variables as predictors of composite airway eosinophil status (eosinophil low = sputum eosinophils <3% and biopsy eosinophils <22/mm2; eosinophil high = sputum eosinophils >3% or biopsy eosinophils >22/mm2).