Figure 1.

Effects of phlorizin on bodyweight, FBG, and AGEs in db/db mice. Comparisons of (A) bodyweight, (B) fasting blood glucose (FBG), and (C) advanced glycation end products (AGEs) among CC group, DM group and DMT group. A: The bodyweight of DM group was higher than that of CC group (**p<0.01), phlorizin significantly reduced bodyweight of db/db mice (##p<0.01). B: Treatment with phlorizin caused a elevated decrease in FBG (##p<0.01). C: Diabetes increased the level of AGES, while phlorizin treatment significantly reduced the diabetes-induced increase in AGES (##p<0.01). The abbreviations used are as follows: control db/m group (CC), untreated db/db group (DM), phlorizin treated db/db group (DMT). All data are expressed as the mean±standard deviation (SD; n=8/ each group, one way-ANOVA, Tukey test).