Table 2.
Growth characteristics of MSC from different sources.
| Cell type | Source | Isolation yield | Doubling time | Clonogenic efficiency | Senescence passage |
|---|---|---|---|---|---|
| BM-MSC | Bone marrow aspirate | 60–600 cells from 1 mL of blood [41] | 61.2 h [29] | 3.9%* | 7 [32] |
| PB-MSC | Peripheral blood | 1 to 13 MSC from 1 million of mononuclear cells [11] | N/A | N/A | N/A |
| DPSC | Deciduous and adult teeth | N/A | 30 h [30] | N/A | N/A |
| UC-MSC | Umbilical cord of newborns | 5 · 104–5 · 105 cells from 1 cm3 of umbilical cord tissue [42] | 24 h [31] | N/A | 16 [31] |
| AT-MSC | Liposuction, lipectomy, and lipoplasty | 5 · 103 cells from 1 g of tissue [11] | 45.2 h [29] | 10% [25] | 8 [32] |
| EDT-MSC | Decidual tissue | Variable‡ | 27.6 h‡ | 14.4%‡ | 26‡ |
Comparison between growth parameters of MSC from different sources. BM-MSC: bone marrow MSC; PB-MSC: peripheral blood MSC; DPSC: dental pulp stromal cells; UC-MSC: umbilical cord MSC; AT-MSC: adipose tissue MSC; EDT-MSC: decidual tissue MSC.*Unpublished data; ‡original data from this study, references.