Table 2. Genotype frequencies of three SNPs in IL1A and IL1B.
| SNPs | Alleles (1>2) | Genotypes | Frequency, % |
P | Pc | OR (95%CI) | ||
|---|---|---|---|---|---|---|---|---|
| Cases (n=169) | Controls (n=390) | |||||||
|
rs2071376 |
(+376 C>A) |
C>A |
AA |
8.3 |
4.9 |
0.117 |
|
1.76 (0.86–3.60) |
| |
|
|
AC |
38.7 |
40.1 |
0.763 |
|
0.94 (0.65–1.37) |
| |
|
|
CC |
53.0 |
55.0 |
0.654 |
|
0.92 (0.64–1.32) |
|
rs1143627 |
(−31 T>C) |
T>C |
CC |
15.4 |
22.2 |
0.064 |
|
0.64 (0.39–1.03) |
| |
|
|
CT |
47.9 |
50.1 |
0.633 |
|
0.92 (0.64–1.31) |
| |
|
|
TT |
36.7 |
27.6 |
0.033 |
0.099 |
1.52 (1.03–2.23) |
|
rs16944 |
(−511 C>T) |
T>C |
CC |
36.7 |
28.6 |
0.058 |
|
1.45 (0.99–2.12) |
| |
|
|
CT |
47.9 |
50.3 |
0.613 |
|
0.91 (0.63–1.31) |
| TT | 15.4 | 21.1 | 0.115 | 0.68 (0.42–1.10) | ||||
1, major allele; 2, minor allele; OR, odds ratio; CI, confidence interval. Individual genotype frequency differences were tested using 2×2 contingency tables for each genotype by combining the remaining genotypes into one category.