Table 3. Haplotype frequencies of rs1143627 and rs16944 in IL1B.
| Haplotypes | Frequency, % |
P | Pc | OR (95%CI) | |
|---|---|---|---|---|---|
| Cases (n=169) | Controls (n=390) | ||||
|
rs1143627-rs16944 |
|
|
|
||
| TC |
60.4 |
47.1 |
4.0×10−5 |
1.6×10−4 |
1.72 (1.33–2.23) |
| CT |
39.1 |
40.6 |
0.643 |
|
0.94 (0.72–1.22) |
| CC |
0.2 |
6.7 |
2.9×10−6 |
1.2×10−5 |
0.03 (0.003–0.31) |
| TT | 0.2 | 5.7 | 2.1×10−5 | 8.4×10−5 | 0.03 (0.003–0.37) |
1, major allele; 2, minor allele; OR, odds ratio; CI, confidence interval. Individual haplotype frequency differences were tested using 2×2 contingency tables for each haplotype by combining the remaining haplotypes into one category.