. Author manuscript; available in PMC: 2013 Apr 15.

Published in final edited form as: Recent Pat Food Nutr Agric. 2012 Apr 1;4(1):50–60. doi: 10.2174/2212798411204010050

Table 5.

Clinical Trials Evaluating the Hypoglycemic Effect of Green Tea

Clinical Trials	Subjects	Treatments	Size	Hypoglycemic effect	Jadad Score	Reference
Fukino Y et al.	Type 2 diabetic patients	Green tea extract containing 544mg polyphenols daily for 2 months	66	No	1	[49]
Mackenzie T et al.	Type 2 diabetic patients	375 or 750mg green tea daily for 3 months	49	No	2	[50]
Nagao T et al.	Type 2 diabetic patients	582.8 or 96.3mg catechin-containing green tea daily for 12 weeks	43	No	0	[51]
Hsu CH et al.	Type 2 diabetic patients	a daily dose of 1500 mg of green tea for 16 weeks	80	No	3	[52]
Fukino Y et al.	Healthy obese volunteers	A pack of green tea powder and extract containing 545mg catechins daily for 2 months	60	Yes/No^a	2	[53]
Venables MC et al.	Healthy volunteers	Green tea extract containing 890 mg polyphenols with moderate exercise	23	Yes	0	[54]
Brown AL et al.	Overweight/obese volunteers	800 mg EGCG daily for 8 weeks	88	No	4	[55]
Josic J et al.	Healthy volunteers	300ml of green tea	14	No	1	[56]

One of the following four measurements was significantly different between the treatment and control group: FBS, HbA1c, postprandial glucose levels and area under curve of blood glucose.