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Repertoire overlap rates at various IC50 nM thresholds
| System | Binding threshold (IC50 nM) | Supertype/cluster repertoire overlap |
||
|---|---|---|---|---|
| Within | Without | Ratio | ||
| Class I | 100 | 29.7 | 1.0 | 28.9 |
| 200 | 31.7 | 1.6 | 20.1 | |
| 500 | 30.4 | 2.6 | 11.9 | |
| 1,000 | 33.3 | 3.6 | 9.2 | |
| 2,000 | 37.3 | 5.3 | 7.1 | |
| 5,000 | 38.9 | 7.8 | 5.0 | |
| Class II | 100 | 19.8 | 8.4 | 2.4 |
| 200 | 27.4 | 12.9 | 2.1 | |
| 500 | 35.1 | 19.9 | 1.8 | |
| 1,000 | 46.4 | 30.8 | 1.5 | |
| 2,000 | 52.8 | 39.9 | 1.3 | |
| 5,000 | 63.6 | 53.4 | 1.2 | |
