Table I.
The recent history of haemophilia treatment.
| Year | Main events |
|---|---|
| 1970s: a golden era | |
| 1970s | Lyophilised plasma-derived coagulation factor concentrates |
| 1977 | Desmopressin |
| 1980s: many shadows, little light | |
| 1982 | Factor IX gene cloned, AIDS |
| 1983 | Early virucidal methods (dry-heating) |
| 1984 | F8 gene cloned, HIV isolated |
| 1985 | Anti-HIV testing |
| 1987 | Safe virus-inactivated plasma-derived coagulation factor concentrates |
| 1989 | Recombinant FVIII products |
| 1990s: a new golden era | |
| 1994 | Immune tolerance |
| 1996 | Recombinant FVIIa, HAART for HIV |
| 1997 | Recombinant FIX |