Table 2.
Standardized mortality ratios for HCV serological groups vs. BC population
| SNR (n=342,325) | MNR (n=73,476) | REAC (n=27,812) | SERO (n=2,408) | All HCV +ve (n=30,220) | ||
|---|---|---|---|---|---|---|
| ICD-10 |
Cause of death |
SMR (95% CI) |
SMR (95% CI) |
SMR (95% CI) |
SMR (95% CI) |
SMR (95% CI) |
| A00-R99; V01-Y98 |
All |
1.44 (1.41 - 1.46) |
2.59 (2.49 - 2.69) |
4.68 (4.50 - 4.86) |
10.13 (8.39 - 12.12) |
4.78 (4.61 - 4.96) |
| B15-B19; B942; C22; K70-K76 |
Liver related |
3.00 (2.77 - 3.24) |
8.44 (7.47 - 9.50) |
23.93 (22.03 - 25.95) |
14.77 (6.36 - 29.09) |
23.73 (21.86 - 25.72) |
| B15-B19; B942 |
Viral hepatitis |
1.04 (0.70 - 1.49) |
2.12 (1.06 - 3.79) |
65.32 (58.51 - 72.70) |
40.31 (13.06 - 93.93) |
64.73 (58.03 - 71.99) |
| C22 |
Liver cancer |
2.64 (2.26 - 3.07) |
4.79 (3.46 - 6.48) |
17.31 (14.10 - 21.04) |
9.02 (0.23 - 50.23) |
17.16 (13.99 - 20.83) |
| K70-K76 |
Liver disease |
3.68 (3.34 - 4.05) |
11.96 (10.43 - 13.65) |
11.09 (9.38 - 13.01) |
6.52 (0.79 - 23.53) |
10.99 (9.31 - 12.88) |
| K70 |
Alcoholic |
3.64 (3.15 - 4.20) |
8.25 (6.50 - 10.33) |
10.58 (8.39 - 13.17) |
5.45 (0.14 - 30.37) |
10.46 (8.30 - 13.00) |
| K71-K76 |
Non-alcoholic |
3.71 (3.25 - 4.21) |
15.65 (13.20 - 18.43) |
11.69 (9.11 - 14.77) |
8.05 (0.20 - 44.85) |
11.62 (9.07 - 14.66) |
| F11-F16; F19; X40-X44; X60-X64; X85; Y10-Y14 |
Drug related |
1.77 (1.56 - 2.00) |
4.54 (3.80 - 5.37) |
19.94 (18.31 - 21.69) |
36.66 (27.12 - 48.46) |
20.72 (19.09 - 22.45) |
| B20-B24 |
HIV |
1.89 (1.48 - 2.37) |
4.08 (2.81 - 5.73) |
26.70 (23.49 - 30.22) |
35.61 (18.94 - 60.89) |
27.03 (23.86 - 30.50) |
| E10-E14 |
Diabetes |
1.86 (1.69 - 2.03) |
5.66 (4.84 - 6.57) |
2.21 (1.52 - 3.10) |
4.49 (0.11 - 24.99) |
2.24 (1.55 - 3.13) |
| N17-N19; I12-I13; N00-N08 |
Renal failure |
2.41 (2.16 - 2.69) |
12.96 (11.12 - 15.03) |
4.58 (3.07 - 6.59) |
14.85 (0.38 - 82.72) |
4.69 (3.16 - 6.70) |
| C00-C97 |
Malignant neoplasm |
1.34 (1.30 - 1.39) |
1.71 (1.57 - 1.86) |
2.35 (2.13 - 2.59) |
2.03 (0.74 - 4.42) |
2.34 (2.12 - 2.58) |
| C22.0; C22.2-C22.9 | Hepatocellular carcinoma | 5.34 (4.47 - 6.34) | 9.58 (6.67 - 13.32) | 36.68 (29.85 - 44.62) | 17.04 (0.43 - 94.89) | 36.27 (29.54 - 44.07) |
Data sources: BCCDC Public Health Microbiology and Reference Laboratory, BC Ministry of Health Services, and BC Vital Statistics Agency.
SNR=single non-reactive; MNR=multiple non-reactive; REAC=reactive at first test; SERO=seroconverter; SMR=standardized mortality ratio.