Figure 4.

Sensitivity of parental HUH-wt and isolated HUH-REISO cells towards in situ activated CPA. Parental and isolated cells were treated with different concentrations of CPA for 3 days together with CPA activating cells X39. Proliferation was determined by measuring total DNA content per well. Control experiments were performed in the absence of CPA. Mean values ± SD of four measurements are shown. No significant differences were observed, nevertheless HUH-REISO cells showed higher sensitivity.