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. Author manuscript; available in PMC: 2013 Sep 5.
Published in final edited form as: Cell Metab. 2013 Mar 5;17(3):423–435. doi: 10.1016/j.cmet.2013.01.016

Figure 5. TLE3 modulates the induction of the thermogenic gene program in inguinal WAT.

Figure 5

A. Immunoblot analysis of TLE3 protein levels in various adipose depots from WT C57Bl/6 mice. B. H&E staining of representative inguinal WAT sections from Cre-negative and Cre-positive TLE3F/F mice. C. Realtime PCR analysis of gene expression in inguinal and epididymal WAT from control and Adn-Cre/TLE3F/F mice fed high-fat diet for 13 wks. N=7–11. D. H&E staining of representative inguinal WAT sections from aP2-TLE Tg and littermate controls (N=3–4) treated for 3 days with 1 mg/kg/day CL-316,243 (CL). E. Real-time PCR analysis of gene expression from inguinal WAT from aP2-TLE Tg and littermate controls treated for 3 days with 10 μM CL-316,243. *P < 0.05. Data are presented as mean +/− SEM (N=3).