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. 2013 Apr 15;8(4):e61085. doi: 10.1371/journal.pone.0061085

Figure 4. Effect of NEM on the cell distribution of wild-type and mutant caspase- 2.

Figure 4

Shown is the distribution of wild-type GFP-Caspase-2 (GFP-C2-WT) (A), and mutant GFP-caspase-2 (GFP-C2-MUT) (B) between nuclear and extra-nuclear fractions of cells without (−) or with (+) NEM (7.5 mM) pre-treatment for 10 min prior to cell lysis. Also shown in both panels is the distribution of endogenously expressed caspase-2 in response to NEM pre-treatment in the same cells. The numbers on the right of the panels reflect the gel migration of the 40 kDa and 70 kDa protein markers.