Table 2. Correlation between FoxP3+ tumor-infiltrating lymphocyte (TIL) density in stromal compartment of tumor center and clinicopathological variables.
% of FoxP3+ TILs in stromal tumor center | p | ||
Age | 0.76 | ||
>60 years | 0.58±0.27 | ||
≤60 years | 0.62±0.33 | ||
Tumor differentiation | 0.36 | ||
well/moderate | 0.61±0.28 | ||
poor | 0.48±0.14 | ||
Tumor location | 0.21 | ||
rectal/left colon | 0.47±0.19 | ||
right colon | 0.62±0.26 | ||
Wall invasion | 0.01 | ||
T1–3 | 0.69±0.31 | ||
T4 | 0.40±0.08 | ||
Node invasion | <0.001 | ||
N0 | 0.76±0.30 | ||
N+ | 0.34±0.06 | ||
TNM stage | 0.001 | ||
I–II | 0.78±0.31 | ||
III–IV | 0.36±0.07 | ||
VELIPI | 0.002 | ||
no | 0.84±0.34 | ||
yes | 0.41±0.08 |
TILs: tumor-infiltrating lymphocytes, VELIPI: vascular emboli or lymphatic invasion or perineural invasion.