Table 1. Clinical characteristics of the study population.
| Variables | Cases (n = 823) | Controls (n = 823) | P * | ||
| No. | % | No. | % | ||
| Ages (mean, range) | 50.1, 23∼83 | 50.0, 23∼83 | |||
| ≤50 | 453 | 55.0 | 455 | 55.3 | 0.921 |
| >50 | 370 | 45.0 | 368 | 44.7 | |
| Menarche ages (years) | |||||
| ≤13 | 126 | 15.3 | 133 | 16.2 | 0.2189 |
| 14∼16 | 361 | 43.9 | 442 | 53.7 | |
| ≥17 | 117 | 14.2 | 94 | 11.4 | |
| NA | 219 | 26.6 | 154 | 18.7 | |
| Childbearing | |||||
| 0 | 22 | 2.7 | 34 | 4.1 | 0.0471 |
| 1 | 442 | 53.7 | 511 | 62.1 | |
| 2 | 158 | 19.2 | 138 | 16.8 | |
| ≥3 | 57 | 6.9 | 63 | 7.7 | |
| NA | 144 | 17.5 | 77 | 9.4 | |
| Status menopausal | |||||
| Premenopause | 388 | 47.1 | 480 | 58.3 | 0.004 |
| Postmenopause | 330 | 40.1 | 302 | 36.7 | |
| NA | 105 | 12.8 | 41 | 5.0 | |
| Diabetes mellitus | |||||
| No | 728 | 88.5 | 769 | 93.4 | 0.954 |
| Yes | 43 | 5.2 | 46 | 5.6 | |
| NA | 52 | 6.3 | 8 | 1.0 | |
| Hypertension | |||||
| No | 664 | 80.7 | 673 | 81.8 | 0.036 |
| Yes | 107 | 13.0 | 145 | 17.6 | |
| NA | 52 | 6.4 | 5 | 0.6 | |
*
Nonparametric rank test for menarche age and childbearing distribution between cases and controls; Two-sided x2 test for other variables distribution between cases and controls; NA, not available.