Table 5.
Odds ratio (OR ) (95% CI) (p -value) for SNP interactions in SNP (3, 4) combinations
| |
Statistics |
CXCR4* |
|||
|---|---|---|---|---|---|
|
Genotypes (X) | |||||
| CC | CT | TT | |||
|
KITLG * |
GG |
ORa |
0.657 |
1.557 |
1.528 |
| Genotypes (Y) |
CI |
0.459-0.940 |
0.936-2.590 |
0.414-5.636 |
|
|
p-value |
0.025 |
0.110 |
0.719 |
||
|
(Ca./Co.) |
(69/137) |
(33/34) |
(4/4) |
||
| AG |
ORa |
1.092 |
1.222 |
1.012 |
|
|
CI |
0.757-1.576 |
0.712-2.098 |
0.201-5.111 |
||
|
p-value |
0.639 |
0.484 |
1.000 |
||
|
(Ca./Co.) |
(70/100) |
(26/33) |
(2/3) |
||
| AA |
ORa |
1.076 |
1.012 |
N.E |
|
|
CI |
0.511-2.266 |
0.303-3.382 |
|
||
|
p-value |
0.848 |
1.000 |
|
||
| (Ca./Co.) | (12/17) | (4/6) | |||
NOTE - *: SNPs (3, 4) pair with its corresponding genotypes CXCR4-rs2228014-genotype X and KITLG-rs10506957-genotype Y; a: OR in reference to the other group (1.000); CI: Confidence Interval; Ca.: case; Co.: control; N.E: Not estimable.