Table 1.
Allelic frequency of the EGFR 3′UTR polyA repeat in CRC patients and controlsa
| |
|
|
|
|
|
|
|
|
|---|---|---|---|---|---|---|---|---|
| |
Controls |
|
|
|
|
Patients |
|
|
| |
|
|
Group 1 |
|
Group 2 |
Group 3 |
Group 4 |
Total |
| MSS | MSI | Total | ||||||
| Number |
170 |
99 |
80 |
179 |
62 |
100 |
88 |
429 |
| Age range (median) |
46–92 (72) |
66–88 (67) |
25–99 (71) |
25–99 (71) |
46–62 (52) |
19–66 (42) |
70–92 (75) |
25–99 (62) |
| A12 |
0.6% (0–2) |
- |
- |
- |
- |
1% (0–4) |
- |
0.2%(0–1) |
| A13 |
76.5% (71–81) |
70.7% (64–77) |
73.7% (66–80) |
72.1% (67–77) |
74.2% (65–81) |
73% (66–79) |
73.3% (66–79) |
72.8% (70–76) |
| A14 |
22.9% (18–28) |
29.3% (23–36) |
26.3% (20–34) |
27.9% (23–33) |
25.8% (18–34) |
26% (20–33) |
26.7% (20–34) |
26.9% (24–30) |
| p valueb | 0.15 | 0.46 | 0.12 | 0.90 | 0.97 | 0.30 | 0.19 |
a For each allelic frequency, confidence interval is given in brackets.
b The p value in each patient group corresponds to the comparison with controls (chi-2 test).