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. 2013 Feb 8;10(1):2. doi: 10.1186/1559-0275-10-2

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Copyright ©2013 Cho et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Top three networks that are potentially disrupted in amniocytes affected with Down syndrome. (A) A network containing 34 associated proteins, 28 of which were identified in our list of 904 proteins. This network is involved in infection mechanism, cellular assembly and organization, and cardiovascular diseases. (B) A network containing 35 associated proteins, 30 of which were identified in our list of 904 proteins. This network is involved in cell morphology, hematological system development and function, and humoral immune response. (C) A network with 35 associated proteins, 29 of which were identified in our list of 904 proteins. This network is involved in cellular assembly and organization, lipid metabolism, and organismal development.