Table 2.
Proteins that show increased expression in T21 amniocytes (n = 31)
| Gene name | Protein name | Ratio (H/L)1 |
|---|---|---|
| AK6 |
Adenylate kinase isoenzyme 6 |
2.70 |
| AMIGO2 |
Amphoterin-induced protein 2 |
8.92 |
| ARSA |
Arylsulfatase A |
1.71 |
| CD9 |
CD9 antigen |
2.48 |
| CNN3 |
Calponin-3 |
1.82 |
| COL8A1 |
Collagen alpha-1(VIII) chain |
1.93 |
| CPA4 |
Carboxypeptidase A4 |
4.84 |
| CRYAB |
Alpha-crystallin B chain |
2.70 |
| CTSZ |
Cathepsin Z |
1.96 |
| DDAH1 |
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 |
2.50 |
| DNPEP |
Aspartyl aminopeptidase |
6.19 |
| DPP7 |
Dipeptidyl-peptidase 2 |
2.31 |
| GREM1 |
Gremlin-1 |
2.78 |
| LCRMP |
Collapsin response mediator protein 4 long variant |
4.38 |
| LPCAT2 |
Lysophosphatidylcholine acyltransferase 2 |
2.51 |
| MFI2 |
Melanotransferrin |
2.91 |
| MYH10 |
Myosin-10 |
2.47 |
| NAAA |
N-acylethanolamine-hydrolyzing acid amidase |
2.83 |
| NAGLU |
Alpha-N-acetylglucosaminidase |
1.73 |
| P4HA1 |
Prolyl 4-hydroxylase subunit alpha-1 |
1.98 |
| PFKL |
6-phosphofructokinase, liver type |
1.98 |
| PLOD2 |
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 |
7.77 |
| PPME1 |
Protein phosphatase methylesterase 1 |
1.82 |
| PYGL |
Glycogen phosphorylase, liver form |
1.81 |
| S100A10 |
Protein S100-A10 |
2.34 |
| SFXN1 |
Sideroflexin-1 |
1.71 |
| SIAE |
Sialate O-acetylesterase |
1.87 |
| SLC25A4 |
ADP/ATP translocase 1 |
2.24 |
| SOD1 |
Superoxide dismutase [Cu-Zn] |
1.91 |
| TPM2 |
Tropomyosin beta chain |
2.70 |
| UAP1 | UDP-N-acetylhexosamine pyrophosphorylase | 1.96 |
1. Heavy/light ratio with SILAC method, calculated as the average of three experimental pairs when available. Only proteins which showed increased ratio for different peptides, as well as consistency in the pattern of expression of experimental pairs were selected.