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. 2013 Jan 4;13(1):17–28. doi: 10.1007/s40268-012-0001-5

Fig. 2.

Fig. 2

Mean (±standard deviation) [n = 6] log-linear plasma concentration–time curves of total radioactivity; unchanged bendamustine; and the metabolites γ-hydroxy-bendamustine, N-desmethyl-bendamustine, and dihydroxy bendamustine up to 24 hours after the start of a 60-minute (120 mg/m2, 80–95 μCi) 14C-bendamustine hydrochloride infusion. HP2 dihydroxy bendamustine, M3 γ-hydroxy-bendamustine, M4 N-desmethyl-bendamustine, TRA total radioactivity