Figure 5.

A model for the mechanism of remodelling of chromatin higher order structure by nucleosome-binding proteins. K_GS is the equilibrium constant for the ground state H4 tail–acidic patch interaction. K₁ is the equilibrium constant for the interaction of nucleosome-binding protein 1 with the acidic patch. K₂ is the equilibrium constant for the interaction of nucleosome-binding protein 2 with the acidic patch. The specific chromatin structure induced by a particular nucleosome-binding protein can range from completely decondensed to hypercondensed. See text for details.