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. Author manuscript; available in PMC: 2013 Apr 16.
Published in final edited form as: Sci Transl Med. 2012 Jan 4;4(115):115ra2. doi: 10.1126/scitranslmed.3002925

Fig. 3.

Fig. 3

Dose-response immunogenicity of chimpanzee adenovirus in mice and macaques. Immunological potency of chimpanzee Ad vectors encoding for HIV-1 gag in BALB/c mice (A) was measured as described in Fig. 1. Data are shown as the reciprocal of minimal dose. The adenovirus serogroups are shown with different bar colours (white=group B, black=group C, light gray=group E).

Immunological potency of human Ad vectors in macaques (B). Three animals per group were vaccinated intramuscularly with 1010 and 108 vp of each Ad vector encoding for HIV-1 gag. Data are expressed as IFNγ SFC per million PBMC. The mean responses + SEM are shown for each immunization group.