Table 5.

Poisson regression model of risk factors for mortality among adults with sickle cell disease

Variable	RR	CI
Age* (years)
31–40	1.08	0.42–2.77
41–50	1.55	0.65–3.69
51–60	0.52	0.06–4.77
> 60	1.03	0.16–6.55
Female	0.56	0.27–1.18
Sickle variant genotype	0.57	0.21–1.58
Venous thromboembolism**	3.63‡	1.66–7.92
End-stage renal disease	3.03†	1.16–7.93
Avascular necrosis	0.58	0.26–1.28
Stroke	1.47	0.62–3.45
Leg ulcer	1.00	0.29–3.49
Tricuspid regurgitant jet velocity ≥ 2.5 m/s	3.40‡	1.47–7.87

RR = relative risk, CI = 95% confidence interval.

^*Reference age category is 18–30 years.

^†p < 0.05,

^‡p < 0.01

^**Does not include catheter-related events.