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. 2013 Mar 5;70(3):161–177. doi: 10.1002/cm.21097

Table V.

Percentages of Molecules that Entered FA Zones via Lateral Diffusion after Binding to the PM Outside FA Zones or Directly Arrived in the FA Zone from the Cytoplasm. Unlike the Values in Table IV, these Percentages were Separately Evaluated for Molecules that Exhibited at Least One TALL Period + the All-time Immobile Mode and for those Exhibited the All-time Mobile Mode

Molecules that exhibited TALL and the all-time immobile mode Molecules that exhibited the all-time mobile mode


Molecules Via PM Direct Via PM Direct
All molecules that entered the FA zone (%molecules)
WT 5.0 ± 0.2 6.4 ± 0.8 65.2 ± 4.8 23.4 ± 4.1
G12V 16.3 ± 1.1 13.0 ± 3.2 51.8 ± 5.1 18.9 ± 1.8
Tail 3.3 ± 0.9 2.0 ± 0.2 74.9 ± 1.1 19.8 ± 0.3
Molecules that exhibited TALL or immobile periods longer than 0.48 s in the FA zone (%molecules)
WT 1.6 ± 0.7 2.1 ± 1.2 68.7 ± 4.9 27.7 ± 4.8
G12V 8.5 ± 1.3 5.5 ± 1.4 59.6 ± 5.7 26.4 ± 3.6
Tail 0.7 ± 0.1 0.8 ± 0.1 77.5 ± 0.3 21.1 ± 0.3

The period of 0.48 s was selected because it was the exponential lifetime of TALL events for G12V, which is constitutively active.