Table 2.

Reports on efficacy of deferiprone on hepatic iron load.

Liver iron concentration (mg/g dry weight)	Type of study	Deferiprone group		Deferoxamine group		p	Reported outcome variable
		n	Outcome	n	Outcome
Using liver biopsy
Maggio et al. [2002]	Randomized controlled trial	20	1.02 (3.51)	15	0.35 (0.52)	0.44	Difference in mean (SD)
Pennell et al. [2006]	Randomized controlled trial	29	0.93 (2.9)	32	1.54 (2.5)	0.4	Difference in mean (SD)
Normal range 0.35–1.36 mg/g dry weight
Using MRI T2*
Anderson et al. [2002]	Case control	15	5.1 (2.8–10.0)	30	3.5 (2.7–4.6)	0.03	Median (IQR) (mg/g dry weight)
Perifanis et al. [2007]	Retrospective	19	3.29 (2.5)	23	8.16 (8.4)	0.014	Mean (SD) (ms)
Normal range 0.35–1.36 mg/g dry weight
Normal range >6.7 ms

IQR, interquartile range; MRI, magnetic resonance imaging; SD, standard deviation.