Table 8.
The hazard ratios and 95% confidence intervals (CIs) for mortality based on univariate and multivariate Cox analysis in procalcitonin-positive patients
| Parameter | Hazard ratio | 95% CI | P | |
|---|---|---|---|---|
|
| ||||
| Low | High | |||
| Univariate | ||||
| Male | 1.246 | 0.583 | 2.682 | 0.570 |
| Age | 1.030 | 0.999 | 1.062 | 0.056 |
| Indirect lung injury | 1.289 | 0.610 | 2.725 | 0.506 |
| Number of organ failure | 2.616 | 1.616 | 4.234 | <0.001 |
| Administration of sivelestat | 0.409 | 0.194 | 0.862 | 0.019 |
| Administration of steroid | 0.942 | 0.446 | 1.992 | 0.876 |
| SOFA score | 1.173 | 1.091 | 1.261 | <0.001 |
| GOCA score | 1.511 | 1.253 | 1.822 | <0.001 |
| SIRS score | 1.451 | 0.841 | 2.504 | 0.181 |
| DIC score | 1.269 | 1.092 | 1.475 | 0.002 |
| PaO2/FIO2 ratio | 1.003 | 0.997 | 1.010 | 0.323 |
| WBC | 1.000 | 1.000 | 1.000 | 0.582 |
| CRP | 0.981 | 0.947 | 1.017 | 0.295 |
| Multivariate | ||||
| Number of organ failure | 1.275 | 0.635 | 2.561 | 0.494 |
| Administration of sivelestat | 0.422 | 0.194 | 0.919 | 0.030 |
| SOFA score | 1.001 | 0.868 | 1.154 | 0.992 |
| GOCA score | 1.365 | 0.959 | 1.941 | 0.084 |
| DIC score | 1.096 | 0.917 | 1.310 | 0.315 |
Abbreviations: ALI, acute lung injury; SOFA score, sequential organ failure assessment score; GOCA score, gas exchange, organ failure, cause, associated disease score; SIRS, systemic inflammatory response syndrome; DIC, disseminated intravascular coagulation; WBC, white blood cell; CRP, C-reactive protein.