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Pathway analysis of peripheral blood mononuclear cell gene expression in subjects with chronic spinal cord injury (SCI) compared with subjects with no SCI. The network depicted is composed of 29 genes related to B-cell development, activation, and proliferation. The nuclear factor-kappaB (NF-κB) protein complex is the central component of this network. B-cell maturation antigen (BCMA), a proliferation-inducing ligand (APRIL), and B-cell–activating factor (BAFF) are highlighted.
