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B-cell maturation antigen (BCMA), a proliferation-inducing ligand (APRIL), and B-cell–activating factor (BAFF) are upregulated in chronic spinal cord injury (SCI). mRNA from peripheral blood mononuclear cells was subjected to quantitative polymerase chain reaction amplification analysis. BCMA, APRIL, and BAFF are significantly up-regulated in SCI, compared with uninjured controls (BCMA: 3.6 fold; APRIL: 3.2 fold, and BAFF: 2.0 fold; p<0.05).
