FIG. 1.

Assessments of volitional and reflexive motor behaviors following administration of serotonergic medication in patients with motor incomplete spinal cord injury (SCI). (A–C) Median Lower Extremity Motor Score (LEMS), modified Ashworth assessment (mAsh) and Spinal Cord Assessment Tools for Spastic Reflexes (SCATS) scores are shown during baseline conditions and following either serotonin (5-HT)-agonist (8 mg cyproheptadine) or a selective 5-HT reuptake inhibitor (SSRI) (10 mg escitalopram). (D–F) A median change of 1.25–3.5 is observed when individual change scores are assessed. Dashed line indicates no change from baseline and is provided for visual reference. *p<0.05; **p<0.01.