Table 3.
GT subcompartment | Overall probability of shedding | Overall probability of shedding with PVL ≤80 | Overall probability of shedding with PVL>80 | Between subject OR of shedding PVL>80 vs. PVL ≤80 at baselinea | Within-subject OR of shedding when PVL >80 vs. PVL ≤80 at follow-upb |
---|---|---|---|---|---|
Ectocervix | 0.25 (0.15, 0.39) | 0.05 (0.01, 0.28) | 0.41 (0.26, 0.59) | 4.8 (0.66, 35.4)3 | 17.0 (1.8, 158.5)c |
Endocervix | 0.21 (0.12, 0.35) | 0.05 (0.02, 0.17) | 0.34 (0.19, 0.53) | 3.7 (0.66, 21.0)3 | 6.2 (1.03, 37.5)c |
Vagina | 0.23 (0.13, 0.39) | 0.04 (0.01, 0.16) | 0.37 (0.22, 0.55) | 5.5 (1.4, 22.7)4 | 32.2 (5.2, 199.4)d |
At least one subcompartment | 0.31 (0.21, 0.45) | 0.11 (0.03, 0.31) | 0.47 (0.35, 0.60) | 2.6 (0.80, 8.7)4 | 11.0 (3.1, 38.7)d |
Between-subject or cross-sectional effect: ratio of the odds of GT shedding when PVL>80 versus PVL ≤80 for women with PVL ≤80 at baseline compared to women with PVL>80 at baseline.
Within-subject or longitudinal effect: odds ratio of GT shedding for women who transition from PVL ≤80 at baseline to PVL>80 at follow-up.
Model adjusted for baseline CD4, change in CD4, baseline BV, change in BV from baseline.
Model adjusted for baseline CD4, change in CD4, baseline BV, change in BV from baseline, and hysterectomy status (yes/no).
OR, odds ratio; BV, bacterial vaginosis.