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. 2013 Apr;22(4):330–338. doi: 10.1089/jwh.2012.3849

Table 3.

Probability (95% CI) of Having HIV-1 RNA Detected in the Genital Tract over All Visits and Stratified When Plasma Viral Load Was Detectable and Undetectable, and the Between-Subject and Within-Subject Odds Ratios of Having Genital Tract Shedding When Plasma Viral Load is Detectable Versus Undetectable, at Visits ≥30 Days after Changing Highly Active Antiretroviral Therapy Regimens

GT subcompartment Overall probability of shedding Overall probability of shedding with PVL ≤80 Overall probability of shedding with PVL>80 Between subject OR of shedding PVL>80 vs. PVL ≤80 at baselinea Within-subject OR of shedding when PVL >80 vs. PVL ≤80 at follow-upb
Ectocervix 0.25 (0.15, 0.39) 0.05 (0.01, 0.28) 0.41 (0.26, 0.59) 4.8 (0.66, 35.4)3 17.0 (1.8, 158.5)c
Endocervix 0.21 (0.12, 0.35) 0.05 (0.02, 0.17) 0.34 (0.19, 0.53) 3.7 (0.66, 21.0)3 6.2 (1.03, 37.5)c
Vagina 0.23 (0.13, 0.39) 0.04 (0.01, 0.16) 0.37 (0.22, 0.55) 5.5 (1.4, 22.7)4 32.2 (5.2, 199.4)d
At least one subcompartment 0.31 (0.21, 0.45) 0.11 (0.03, 0.31) 0.47 (0.35, 0.60) 2.6 (0.80, 8.7)4 11.0 (3.1, 38.7)d
a

Between-subject or cross-sectional effect: ratio of the odds of GT shedding when PVL>80 versus PVL ≤80 for women with PVL ≤80 at baseline compared to women with PVL>80 at baseline.

b

Within-subject or longitudinal effect: odds ratio of GT shedding for women who transition from PVL ≤80 at baseline to PVL>80 at follow-up.

c

Model adjusted for baseline CD4, change in CD4, baseline BV, change in BV from baseline.

d

Model adjusted for baseline CD4, change in CD4, baseline BV, change in BV from baseline, and hysterectomy status (yes/no).

OR, odds ratio; BV, bacterial vaginosis.