. 2013 Apr;22(4):330–338. doi: 10.1089/jwh.2012.3849

Table 4.

Probability (96% CI) of Having HIV-1 RNA Detected in the Genital Tract over All Visits and Stratified When Plasma Viral Load Was Detectable and Undetectable, and the Between-Subject and Within-Subject Odds Ratios of Having Genital Tract Shedding when Plasma Viral Load is Detectable Versus Undetectable, at Visits ≥60 Days after Changing Highly Active Antiretroviral Therapy Regimens

GT subcompartment	Overall probability of shedding	Overall probability of shedding with PVL ≤80	Overall probability of shedding with PVL>80	Between subject OR of shedding PVL>80 vs. PVL ≤80 at baseline^a	Within-subject OR of shedding when PVL>80 vs. PVL ≤80 at follow-up^b
Ectocervix	0.23 (0.14, 0.37)	0.04 (0.01, 0.21)	0.40 (0.25, 0.57)	15.1 (1.5, 156.6)^c	20.1 (0.86, 466.4)^c
Endocervix	0.21 (0.11, 0.34)	0.06 (0.02, 0.18)	0.33 (0.18, 0.52)	6.9 (0.53, 88.8)^c	4.8 (1.01, 22.9)^c
Vagina	0.22 (0.13, 0.37)	0.02 (0.003, 0.10)	0.37 (0.22, 0.54)	9.3 (0.84, 101.5)^d	27.6 (2.9, 266.8)^d
At least one subcompartment	0.32 (0.21, 0.45)	0.10 (0.03, 0.28)	0.50 (0.38, 0.62)	6.5 (2.6, 16.8)^d	6.5 (3.0, 14.1)^d

^{^a}

Between-subject or cross-sectional effect: ratio of the odds of GT shedding when PVL>80 vs. PVL ≤80 for women with PVL ≤80 at baseline compared to women with PVL>80 at baseline.

^{^b}

Within-subject or longitudinal effect: odds ratio of GT shedding for women who transition from PVL ≤80 at baseline to PVL>80 at follow-up.

^{^c}

Model adjusted for baseline CD4, change in CD4, baseline BV, and change in BV from baseline.

^{^d}

Model adjusted for hysterectomy status (yes/no), baseline CD4, change in CD4, baseline BV, and change in BV from baseline.