Table 1.
Variable | Category of variable distribution | p-trend § |
p-
heterogeneity ^ |
||||
---|---|---|---|---|---|---|---|
| |||||||
1 | 2 | 3 | 4 | 5 | |||
Body Mass Index
*
in 1992 # |
18.5 -23 | 23-24.9 | 25-26.9 | 27-29.9 | >=30 | ||
Men | |||||||
No. cases | 62 | 88 | 122 | 95 | 46 | ||
No. PY | 104352 | 167751 | 201441 | 185469 | 106924 | ||
RR1 | 1.0 (Ref) | 0.91 (0.66, 1.27) | 1.11 (0.82, 1.52) | 0.98 (0.71, 1.36) | 0.86 (0.58, 1.27) | ||
RR2 | 1.0 (Ref) | 0.93 (0.67, 1.28) | 1.17 (0.86, 1.59) | 1.06 (0.77, 1.47) | 0.98 (0.66, 1.46) | 0.80 | |
Women | |||||||
No. cases | 72 | 52 | 28 | 41 | 33 | ||
No. PY | 300682 | 199658 | 156020 | 150220 | 148417 | ||
RR1 | 1.0 (Ref) | 1.06 (0.74, 1.52) | 0.71 (0.46, 1.11) | 1.10 (0.75, 1.61) | 0.96 (0.63, 1.45) | ||
RR2 | 1.0 (Ref) | 1.08 (0.76, 1.55) | 0.73 (0.47, 1.14) | 1.18 (0.80, 1.74) | 1.02 (0.66, 1.56) | 0.91 | |
Men and Women | |||||||
RR2 | 1.00 (0.78, 1.26) | 0.95 (0.60, 1.50) | 1.11 (0.86, 1.42) | 1.00 (0.75, 1.34) | 0.79 | 0.94 | |
Body Mass Index at
age 18 |
<20 | 20-22.4 | 22.5-24.9 | 25-26.9 | >=27 | ||
Men | |||||||
No. cases | 106 | 160 | 90 | 37 | 18 | ||
No. PY | 203070 | 276690 | 174326 | 67257 | 38329 | ||
RR1 | 1.0 (Ref) | 1.13 (0.88, 1.45) | 1.05 (0.79, 1.39) | 1.16 (0.79, 1.69) | 1.04 (0.63, 1.72) | ||
RR2 | 1.0 (Ref) | 1.12 (0.87, 1.43) | 1.05 (0.79, 1.39) | 1.19 (0.82, 1.74) | 1.06 (0.64, 1.74) | 0.61 | |
Women | |||||||
No. cases | 99 | 82 | 34 | 9 | 8 | ||
No. PY | 429135 | 359543 | 120963 | 29410 | 28460 | ||
RR1 | 1.0 (Ref) | 1.01 (0.75, 1.36) | 1.24 (0.83, 1.83) | 1.43 (0.72, 2.85) | 1.35 (0.65, 2.80) | ||
RR2 | 1.0 (Ref) | 1.02 (0.76, 1.37) | 1.23 (0.83, 1.83) | 1.43 (0.71, 2.84) | 1.36 (0.66, 2.82) | 0.17 | |
Men and Women | |||||||
RR2 | 1.08 (0.89, 1.30) | 1.11 (0.88, 1.40) | 1.24 (0.89, 1.73) | 1.15 (0.76, 1.73) | 0.23 | 0.40 | |
Weight change between age 18 and 1992# (pounds**) |
5lb loss to 5lb
gain |
5-14.9lb gain | 15-24.9lb gain | 25-44.9lb gain | >=45lb gain | ||
Men | |||||||
No. cases | 30 | 49 | 76 | 137 | 105 | ||
No. PY | 30920 | 96759 | 132361 | 252474 | 217365 | ||
RR1 | 1.0 (Ref) | 0.51 (0.32, 0.81) | 0.59 (0.38, 0.89) | 0.57 (0.38, 0.84) | 0.53 (0.35, 0.80) | ||
RR2 | 1.0 (Ref) | 0.51 (0.32, 0.80) | 0.58 (0.37, 0.89) | 0.56 (0.37, 0.84) | 0.54 (0.35, 0.85) | 0.36 | |
Women | |||||||
No. cases | 20 | 41 | 43 | 58 | 52 | ||
No. PY | 66150 | 151042 | 174495 | 285362 | 229905 | ||
RR1 | 1.0 (Ref) | 0.92 (0.54, 1.58) | 0.83 (0.49, 1.41) | 0.68 (0.41, 1.13) | 0.74 (0.44, 1.25) | ||
RR2 | 1.0 (Ref) | 0.93 (0.54, 1.60) | 0.80 (0.46, 1.40) | 0.63 (0.35, 1.11) | 0.62 (0.32, 1.21) | 0.06 | |
Men and Women | |||||||
RR2 | 0.68 (0.38, 1.22) | 0.65 (0.46, 0.90) | 0.58 (0.42, 0.81) | 0.56 (0.39, 0.82) | 0.08 | 0.26 |
Weight (kg)/height(m)2
study baseline
1 pound = 0.45 kg
*adjusted for age in months and smoking in quintiles of pack years
*adjusted for age in months and smoking in quintiles of pack years, alcohol intake, caffeine intake, calories, dairy intake, physical activity, pesticide exposure and education
trend tests conducted in multivariate models
p-heterogeneity comparing analyses including only men to those including only women