Table 2. Spearman Rank Correlations and Adjusted P Values of Selected Bile Acid Genes and Metabolites.

The Spearman rank correlation values of three critical BA pathway genes and metabolites with the corresponding adjusted p values (in parentheses) is shown. Statistical significance of the correlation is represented by p value ≤ 0.05 and is designated by asterisk (*).

Metabolites	CYP7B1	BAAT	CYP8B1
TCA	0.2664 (0.343)	0.2661 (0.343)	0.0664 (0.858)
TDCA	0.4476 (0.0624)	0.2507 (0.383)	−0.2048 (0.475)
CA	−0.5843 (0.0057)*	−0.3572 (0.164)	0.3062 (0.259)
DCA/CDCA	−0.5489 (0.012)*	−0.4068 (0.0936)	0.1638 (0.581)
GDCA	−0.6013 (0.004)*	−0.4478 (0.0601)	0.4733 (0.0412)*
GCA	0.1445 (0.636)	0.3369 (0.199)	0.3347 (0.202)
GCDCA	0.3524 (0.169)	0.3159 (0.238)	−0.0301 (0.936)
TUCA	−0.0574 (0.864)	−0.2037 (0.475)	0.2138 (0.458)
TUDCA	0.2529 (0.38)	0.0707 (0.851)	−0.0284 (0.942)
GUDCA	0.0272 (0.943)	−0.0036 (0.994)	0.2188 (0.68)
Taurine	0.6838 (0.000581)*	0.3936 (0.107)	−0.3741 (0.132)