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. 2013 Feb 26;41(7):4036–4048. doi: 10.1093/nar/gkt100

Figure 1.

Figure 1.

Type I NRs localize to the PRL array only under dual ligand conditions. (A) Schematic representation of the PRL array that was stably integrated into the PRL-HeLa array cell line along with GFP-ERα. (B) Images of transfected ERα (bottom row) and AR (top row) in PRL HeLa cells treated with 10 nM DHT, 10 nM E2 or E2 + DHT. (C) Images of transfected ERα (bottom row) and GR (top row) in PRL HeLa cells treated with 100 nM Dex, 10 nM E2 or E2 + Dex. (D) Images of transfected ERα (bottom row) and PR-B (top row) in PRL HeLa cells treated with 10 nM R5020, 10 nM E2 or E2 + R5020. (E). Images of transfected ERα (bottom row) and PPARγ (top row) in PRL-HeLa cells treated with 10 nM Rosi, 10 nM E2 or E2 + Rosi. White arrows indicate the location of NR loading onto the PRL array.