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Binding parameters for TMPipEOPP–G-quadruplexes interactions
| G-quadruplexes | Binding stoichiometry of TMPipEOPP to G-quadruplex | Ka (×10−6 M−1)a | Hypochro-micity of the Soret band |
|---|---|---|---|
| Hum24 | 1:2 | 1.1 | 75% |
| KRAS | 1:2 | 2.6 | 86% |
| C-MYC | 1:2 | 1.4 | 81% |
| Hum48 | 1:1.6 | 83% | |
| Hum54 | 1:1.4 | 80% | |
| Hum59 | 1:1 | 0.62 | 80% |
aThe mean value of Scatchard analysis results using the absorption signals at 454 and 695 nm.
