Table 3.

Thermodynamic parameters for G-rich oligonucleotides and the stabilizing abilities of TMPipEOPP to G-quadruplexes

G-quadruplexes	ΔH° (kJ/mol)	ΔS° (J/mol·K)	ΔG°37 (kJ/mol)	T1/2 (°C)
				[TMPipEOPP] (μM)
				0	5
Hum24	−67.45	−208.0	−2.94	51.4	60.6
Hum48	−67.94	−214.8	−1.32	43.5	56.5
Hum54	−72.96	−229.3	−1.83	45.5	57.7
Hum59	−82.79	−258.4	−2.65	47.3	58.1
KRAS	−73.26	−229.0	−2.24	47.8	54.9
C-MYC	−82.21	−264.7	−0.11	37.6	47.1