Table 1.
COPDGene study subjects
| All subjects | Severe emphysema‡ | No emphysema§ | |
|---|---|---|---|
| N |
8517 |
1188 |
5769 |
| Age |
59.6 (9.0) |
65.5 (7.7) |
57.6 (8.6) |
| Sex | |||
| Male |
4535 (53.2%) |
711 (59.8%) |
2849 (49.4%) |
| Female |
3982 (46.8%) |
477 (40.2%) |
2920 (50.6%) |
| Race | |||
| African American |
2668 (31.3%) |
190 (16.0%) |
2156 (37.4%) |
| White |
5849 (68.7%) |
998 (84.0%) |
3613 (62.6%) |
| Current smoking |
4463 (52.4%) |
259 (21.8%) |
3547 (61.5%) |
| Pack-years of smoking |
44.3 (24.8) |
55.4 (27.8) |
40.8 (22.6) |
| GOLD Stage |
[54 missing]† |
[3 missing]† |
[40 missing]† |
| 0 |
3674 (43.4%) |
17 (1.4%) |
3241 (56.6%) |
| 1 |
668 (7.9%) |
47 (4.0%) |
414 (7.2%) |
| 2 |
1636 (19.3%) |
263 (22.2%) |
870 (15.2%) |
| 3 |
965 (11.4%) |
458 (38.7%) |
217 (3.8%) |
| 4 |
502 (5.9%) |
396 (33.4%) |
33 (0.6%) |
| Unclassified* | 1018 (12.0%) | 4 (0.3%) | 954 (16.7%) |
Non-smokers were excluded. Mean (SD) or N (%) is shown.
*Unclassified: FEV1 < 80% predicted with FEV1/FVC > 0.7.
†GOLD Stage is missing in subjects whose spirometry failed quality control.
‡Severe emphysema defined by Insp-950HU > 15% ex-smokers, > 14% current smokers.
§No emphysema defined by Insp-950HU < 5% ex-smokers, < 4% current smokers.