Figure 5. Nmnat2 deletion mutants show substantial neurite protection up to 72 h.
(A) Representative fields of view of distal primary culture SCG neurites 0 and 72 h after neurite cut, labelled by dsRed2 expression and injected with 0.0005 µg/µl EGFP or the relevant Nmnat2-EGFP variant or WldS-EGFP. (B) Quantification of experiment shown in (A). Error bars indicate SEM. * and *** indicate statistically significant difference compared to wild-type Nmnat2 (* p<0.05, *** p<0.001). ## indicates statistically significant difference compared to deletion mutants (## p<0.01).