Figure 1. Genomic structure and organization of zebrafish and mouse ambra1 genes. Plain boxes indicate exons. The coding region is in color and numbered with Roman numerals. Boxes of exon 8 are dashed in transcripts where it may be absent. The positions of the WD40 domain, BECN1 and DYNLL1 binding regions are indicated. Introns, represented as lines, are not drawn to scale, but the corresponding lengths can be found in Table S1 together with the exon sizes. Exons in zebrafish ambra1a and b are similar in size to orthologous exons in mouse Ambra1.