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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: Hum Mutat. 2012 Oct 11;34(1):32–41. doi: 10.1002/humu.22212

Table 1.

Data Sources

ID Data source Experimental method Source Total Genes Long list Medium list Short list Score
DS1 In vitro functional studies, heterologous expression, inhibitors, in situ hybridization Pubmed 181 181 181 85 1.0
DS2 Knockout gene knockout in mouse models MGI 88 88 88 74 1.0
DS3 Disease identification of genes involved in human disease with olfactory phenotype Pubmed OMIM 60 60 60 28 1.0
DS4 Ciliome proteome analysis of rat OSN cilia [Mayer et al., 2009] 377 329 58 24 0–1.0
DS5 OSN microarray genes identified in mouse OSN [Sammeta et al., 2007] 11,596 250 66 17 0–1.0
DS6 OE NGS mouse RNA-seq of mouse OE our experimental data 16,647 250 141 57 0–1.0
DS7 OSN NGS RNA-seq of mouse single OSNs our experimental data 1,000 250 85 32 0–1.0
DS8 OE NGS human RNA-seq of human OE our experimental data 16,647 250 49 16 0–1.0
DS9 Bulb NGS RNA-seq of mouse olfactory bulb our experimental data 16,647 250 86 29 0–1.0
DS10 Linkage Whole genome linkage analysis of anosmic and hyposmic individuals [Gerber et al., 2011; Ghadami et al., 2004; Pinto et al., 2008; Sobin et al., 2006] 596 56 56 8 0.5
DS11 GeneCards Computerized curation of genes, excluding genes present in DS1 GeneCards 260 175 36 8 0.5
Total 1,680 450 136

MGI, Mouse Genome Informatics; NGS, next generation sequencing; OE, olfactory epithelium; OMIM, Online Mendelian Inheritance in Man; OSN, olfactory sensory neuron; RNA-seq, next-generation transcriptome sequencing.